Pub. Date : 2010 Feb 4
PMID : 20132554
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Demethylation agent 5-aza-2"-deoxycytidine (5-aza-dc) selectively inhibits DNA methyltransferases, DNMT3a and DNMT3b, and restored CASP8 and maspin gene expression in breast cancer cells. | Decitabine | caspase 8 | Homo sapiens |
2 | Demethylation agent 5-aza-2"-deoxycytidine (5-aza-dc) selectively inhibits DNA methyltransferases, DNMT3a and DNMT3b, and restored CASP8 and maspin gene expression in breast cancer cells. | Decitabine | caspase 8 | Homo sapiens |
3 | 5-aza-dc also reduced histone H3k9me2 occupancy on CASP8 promoter in SKBR3cells, but not in MCF-7 cells. | Decitabine | caspase 8 | Homo sapiens |