Title : Curcumin attenuates cerebral edema following traumatic brain injury in mice: a possible role for aquaporin-4?

Pub. Date : 2010 May

PMID : 20132469






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The protective effect of curcumin was associated with a significant attenuation in the acute pericontusional expression of interleukin-1beta, a pro-inflammatory cytokine, after injury. Curcumin interleukin 1 beta Mus musculus
2 Notably, curcumin blocked IL-1beta-induced aquaporin-4 expression in cultured astrocytes, an effect mediated, at least in part, by reduced activation of the p50 and p65 subunits of nuclear factor kappaB. Curcumin interleukin 1 beta Mus musculus