Title : Effects of cytochrome p450 inhibitors on itraconazole and fluconazole induced cytotoxicity in hepatocytes.

Pub. Date : 2009

PMID : 20130764






1 Functional Relationships(s)
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1 In vitro incubation of hepatocytes with itraconazole revealed significantly lower viability when compared to fluconazole as assessed by lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase activities. Itraconazole glutamic-oxaloacetic transaminase 2 Rattus norvegicus