Title : Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms.

Pub. Date : 2010 Apr 15

PMID : 20130243






1 Functional Relationships(s)
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1 INCB018424 inhibited interleukin-6 signaling (50% inhibitory concentration [IC(50)] = 281nM), and proliferation of JAK2V617F(+) Ba/F3 cells (IC(50) = 127nM). ruxolitinib interleukin 6 Mus musculus