Title : Disulfide isomerase glucose-regulated protein 58 is required for the nuclear localization and degradation of retinoic acid receptor alpha.

Pub. Date : 2010 Apr

PMID : 20130111






1 Functional Relationships(s)
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1 Moreover, treatment with sulfhydryl-modifying agents that oxidize SH-groups of cysteine residues to disulfide bonds abolished ATRA-mediated RARA nuclear localization, suggesting that the thiol oxidoreductase activity of GRp58 may be required for RARA nuclear import. Disulfides protein disulfide isomerase associated 3 Mus musculus