Title : Delta-aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1).

Pub. Date : 2010 Mar

PMID : 20128809






2 Functional Relationships(s)
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1 KEY RESULTS: ALA inhibited SLC36A1-mediated L-[(3)H]Pro and SLC15A1-mediated [(14)C]Gly-Sar uptake in Caco-2 cell monolayers with IC(50) values of 11.3 and 2.1 mM respectively. Aminolevulinic Acid solute carrier family 15 member 1 Homo sapiens
2 ALA was a substrate for SLC36A1, and the apical absorption in Caco-2 cell was only mediated by SLC36A1 and SLC15A1. Aminolevulinic Acid solute carrier family 15 member 1 Homo sapiens