Pub. Date : 2010 Nov 15
PMID : 20127859
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype. | Benzo(a)pyrene | cytochrome P450, family 27, subfamily b, polypeptide 1 | Mus musculus |
| 2 | Following high dosage of oral BaP (125 mg/kg/day), ablation of the mouse Cyp1a1 gene causes immunosuppression and death within ~28 days, whereas Cyp1(+/+) wild-type mice remain healthy for >12 months on this regimen. | Benzo(a)pyrene | cytochrome P450, family 27, subfamily b, polypeptide 1 | Mus musculus |