Title : Rho-kinase regulates negatively the epidermal growth factor-stimulated colon cancer cell proliferation.

Pub. Date : 2010 Mar

PMID : 20126978






1 Functional Relationships(s)
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1 Interestingly, EGF-induced phosphorylation of both Akt and glycogen synthase kinase-3beta (GSK-3beta), but not p44/p42 mitogen-activated protein (MAP) kinase, were dose-dependently enhanced when the cells were pretreated with Y27632 or fasudil, another Rho-kinase inhibitor. fasudil AKT serine/threonine kinase 1 Homo sapiens