Title : Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors.

Pub. Date : 2010 Feb 15

PMID : 20122835






2 Functional Relationships(s)
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Protein Name
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1 Prostaglandins have a short life in vivo because they are metabolized rapidly by oxidation to 15-ketoprostaglandins catalyzed by a cytosolic enzyme known as NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Prostaglandins 15-hydroxyprostaglandin dehydrogenase Homo sapiens
2 Prostaglandins have a short life in vivo because they are metabolized rapidly by oxidation to 15-ketoprostaglandins catalyzed by a cytosolic enzyme known as NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH). Prostaglandins 15-hydroxyprostaglandin dehydrogenase Homo sapiens