Pub. Date : 2010 Mar 29
PMID : 20121702
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intriguingly, the Ca2+-induced expression of GLO1 was enhanced in the presence of FK506, a potent inhibitor of calcineurin. | Tacrolimus | lactoylglutathione lyase GLO1 | Saccharomyces cerevisiae S288C |
| 2 | Consequently, the Ca2+-induced expression of GLO1 in a mutant that is defective in calcineurin or Crz1, the sole transcription factor downstream of calcineurin, was much greater than that in the wild-type strain even without FK506. | Tacrolimus | lactoylglutathione lyase GLO1 | Saccharomyces cerevisiae S288C |
| 3 | The level of Ca2+-induced expression of GLO1 reached a maximum in cells overexpressing MSN2 even when FK506 was not present, whereas in cells overexpressing CRZ1 the level was greatly reduced and increased markedly when FK506 was present. | Tacrolimus | lactoylglutathione lyase GLO1 | Saccharomyces cerevisiae S288C |
| 4 | The level of Ca2+-induced expression of GLO1 reached a maximum in cells overexpressing MSN2 even when FK506 was not present, whereas in cells overexpressing CRZ1 the level was greatly reduced and increased markedly when FK506 was present. | Tacrolimus | lactoylglutathione lyase GLO1 | Saccharomyces cerevisiae S288C |