Title : Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients.

Pub. Date : 2010

PMID : 20118554






2 Functional Relationships(s)
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1 Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients. Fluvoxamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 Among non-smoker patients, the C/D ratios of fluvoxamine in those with one and two mutated alleles of CYP2D6 were 1.6- and 1.4-fold higher, respectively, than those with no mutated alleles, though the differences among those three genotype groups were not significant. Fluvoxamine cytochrome P450 family 2 subfamily D member 6 Homo sapiens