Title : Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors.

Pub. Date : 2010 Feb 15

PMID : 20117937






1 Functional Relationships(s)
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Protein Name
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1 5-Chloro-6-hydroxy-N-(2-morpholinoethyl)nicotinamide (13) displayed the highest MAO-A inhibitory potency (IC(50)=0.045 microM) and a good selectivity. chloro-6-hydroxy-n-(2-morpholinoethyl)nicotinamide monoamine oxidase A Homo sapiens