Title : Axon degeneration: Mechanisms and implications of a distinct program from cell death.

Pub. Date : 2010 Mar

PMID : 20117162






1 Functional Relationships(s)
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1 The mitochondrial Nmnat3 and cytoplasm-localized mutants of Wld(S) and Nmnat1 have similar or even stronger effect than Wld(S) to delay axon degeneration, which suggest that increased mitochondrial or local NAD synthesis might contribute to the protective function of Wld(S) and Nmnats. NAD nicotinamide nucleotide adenylyltransferase 1 Mus musculus