Pub. Date : 2010 Apr
PMID : 20116423
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Data of Western blot further demonstrated that aspirin treatment caused activation of caspases, down-regulation of Mcl-1 protein, dephosphorylation of ERK-1/2 and AKT, and also IkappaB-alpha proteolysis-dependent NF-kappaB activation in YD-8 cells. | Aspirin | nuclear factor kappa B subunit 1 | Homo sapiens |
2 | These findings collectively suggest that aspirin induces apoptosis in YD-8 cells and the induction may be correlated to activation of caspases, caspase-dependent Mcl-1 proteolysis, inactivation of ERK-1/2 and AKT, and activation of NF-kappaB. | Aspirin | nuclear factor kappa B subunit 1 | Homo sapiens |