Title : Phenobarbital increases rat hepatic prostaglandin F2 alpha, glutathione S-transferase activity and oxidative stress.

Pub. Date : 1991 Jan

PMID : 2011611






4 Functional Relationships(s)
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1 Phenobarbital increases rat hepatic prostaglandin F2 alpha, glutathione S-transferase activity and oxidative stress. Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus
2 PB treatment increased glutathione S-transferase (GST) activity by 80% and prostaglandin (PG) F2 alpha levels 4-fold (p less than 0.05). Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus
3 PB treatment increased glutathione S-transferase (GST) activity by 80% and prostaglandin (PG) F2 alpha levels 4-fold (p less than 0.05). Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus
4 PB"s effect on PGF2 alpha could be a result of both GST-mediated prostaglandin synthesis and oxidative stress. Phenobarbital hematopoietic prostaglandin D synthase Rattus norvegicus