Title : Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human equilibrative nucleoside transporter and the human facilitative nucleobase transporter.

Pub. Date : 2010 Jan 29

PMID : 20113503






2 Functional Relationships(s)
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1 CONCLUSION: Collectively, the data obtained in this study clearly show that the endogenous host erythrocyte transporters hENT1 and hFNT1, rather than the NPP, are the major route of entry of purine into parasitized RBC. purine solute carrier family 29 member 1 (Augustine blood group) Homo sapiens
2 Inhibitors of hENT1 and hFNT1, as well as the NPP, should be considered in the development of anti-malarials targeted to purine transport. purine solute carrier family 29 member 1 (Augustine blood group) Homo sapiens