Title : Inhibition of citrinin-induced apoptotic biochemical signaling in human hepatoma G2 cells by resveratrol.

Pub. Date : 2009 Jul 29

PMID : 20111678






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Resveratrol inhibited CTN-induced ROS generation, activation of JNK, loss of mitochondrial membrane potential (MMP), as well as activation of caspase-9, caspase-3 and PAK2. Resveratrol mitogen-activated protein kinase 8 Homo sapiens
2 These results collectively demonstrate that CTN stimulates ROS generation and JNK activation for mitochondria-dependent apoptotic signaling in Hep G2 cells, and these apoptotic biochemical events are blocked by pretreatment with resveratrol, which exerts antioxidant effects. Resveratrol mitogen-activated protein kinase 8 Homo sapiens