Pub. Date : 2010 Jun
PMID : 20107853
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we show that FSK-induced supporting cell proliferation is mediated by cell-specific accumulation of cyclic adenosine monophosphate (cAMP) in avian supporting cells and the extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) pathway. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |
2 | Here, we show that FSK-induced supporting cell proliferation is mediated by cell-specific accumulation of cyclic adenosine monophosphate (cAMP) in avian supporting cells and the extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) pathway. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |
3 | Here, we show that FSK-induced supporting cell proliferation is mediated by cell-specific accumulation of cyclic adenosine monophosphate (cAMP) in avian supporting cells and the extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) pathway. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |
4 | By a combination of immunostaining and pharmacological analyses, we show that FSK treatment increases cAMP levels in avian auditory supporting cells and that several ERK MAP inhibitors effectively block FSK-induced supporting cell proliferation. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |
5 | Collectively, these data suggest that FSK-induced supporting cell proliferation in the avian auditory epithelium is mediated by increases of cAMP levels in supporting cells and the cell-specific expression of the ERK MAPK family member B-Raf in supporting cells. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |
6 | Collectively, these data suggest that FSK-induced supporting cell proliferation in the avian auditory epithelium is mediated by increases of cAMP levels in supporting cells and the cell-specific expression of the ERK MAPK family member B-Raf in supporting cells. | Colforsin | mitogen-activated protein kinase 1 | Homo sapiens |