Pub. Date : 2010 Apr
PMID : 20107114
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Prostaglandins (PGs), produced by two isoforms of cyclooxygenase (COX), COX-1 and COX-2, are important modulators of renal hemodynamics. | Prostaglandins | cytochrome c oxidase I, mitochondrial | Mus musculus |
2 | Prostaglandins (PGs), produced by two isoforms of cyclooxygenase (COX), COX-1 and COX-2, are important modulators of renal hemodynamics. | Prostaglandins | cytochrome c oxidase I, mitochondrial | Mus musculus |
3 | Genetic deletion of COX-1 enhances COX-2 production of PGs, decreases renal and urinary PGs, and attenuates ANG II-induced hypertension. | Prostaglandins | cytochrome c oxidase I, mitochondrial | Mus musculus |
4 | Genetic deletion of COX-1 enhances COX-2 production of PGs, decreases renal and urinary PGs, and attenuates ANG II-induced hypertension. | Prostaglandins | cytochrome c oxidase I, mitochondrial | Mus musculus |
5 | This study shows that COX-1-generated PGs partially mediate ANG II increases in TGF and that COX-2 PGs offset that effect. | Prostaglandins | cytochrome c oxidase I, mitochondrial | Mus musculus |