Title : HO-1 polymorphism as a genetic determinant behind the malaria resistance afforded by haemolytic disorders.

Pub. Date : 2010 May

PMID : 20106603






1 Functional Relationships(s)
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1 In this context, it has been shown that the rate limiting enzyme heme oxygenase I (HO-1), responsible for the catabolism of the free heme in the body, is an important resistance factor in malaria and is also important in the physiopathology of haemolytic diseases. Heme heme oxygenase 1 Homo sapiens