Title : Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?

Pub. Date : 2010 Sep 6

PMID : 20105433






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rate constants for the inhibition of human AChE by OPs, spontaneous dealkylation and reactivation as well as reactivation by obidoxime and HI 6 of OP-inhibited human AChE were determined. Obidoxime Chloride acetylcholinesterase (Cartwright blood group) Homo sapiens