Pub. Date : 2010 Mar 2
PMID : 20104904
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of several analogues tested, only one novel non-natural nucleoside, 5-cyclohexylindolyl-2"-deoxyribose (5-CHInd), behaves as a P-gp inhibitor. | 5-chind | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Although 5-CHInd is an adenosine analogue that should block the binding of ATP, the non-natural nucleoside surprisingly stimulates the ATPase activity of P-gp in vitro. | 5-chind | ATP binding cassette subfamily B member 1 | Homo sapiens |