Title : Autophagy: polyQ toxic fragment turnover.

Pub. Date : 2010 Feb

PMID : 20104018






2 Functional Relationships(s)
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1 In this study we explore the role for autophagy in the clearance of an N-terminal caspase-7-generated fragment of ataxin-7, a protein with a pathogenic polyglutamine (polyQ) expansion in the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). polyglutamine caspase 7 Mus musculus
2 In this study we explore the role for autophagy in the clearance of an N-terminal caspase-7-generated fragment of ataxin-7, a protein with a pathogenic polyglutamine (polyQ) expansion in the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). polyglutamine caspase 7 Mus musculus