Title : Effect of BMP-9 and its derived peptide on the differentiation of human white preadipocytes.

Pub. Date : 2010 Jun

PMID : 20102315






1 Functional Relationships(s)
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1 Incubation of the cells for 1 h with BMP-2, BMP-9 or pBMP-9 activated the Smad1/5/8 pathway, while incubation for 7 days in adipocyte differentiation (AD) serum-free medium containing ciglitazone and equimolar concentrations of BMP-2, BMP-9 or pBMP-9 enhanced the levels of mRNA of the adipogenic markers aP2 and adipoQ and increased the number of lipid vesicles. pbmp-9 SMAD family member 1 Homo sapiens