Title : Processing of CD109 by furin and its role in the regulation of TGF-beta signaling.

Pub. Date : 2010 Apr 15

PMID : 20101215






2 Functional Relationships(s)
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1 To investigate whether furinase cleavage of CD109 is necessary for its biological activity, we mutated arginine 1273 in the CD109 furinase cleavage motif (amino acid 1270-RRRR-1273) to serine (R1273S). Serine CD109 molecule Homo sapiens
2 To investigate whether furinase cleavage of CD109 is necessary for its biological activity, we mutated arginine 1273 in the CD109 furinase cleavage motif (amino acid 1270-RRRR-1273) to serine (R1273S). Serine CD109 molecule Homo sapiens