Title : Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.

Pub. Date : 2010 May

PMID : 20100815






2 Functional Relationships(s)
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1 When the P450 activities were measured at the whole-cell level, some of the blue colonies, but not the white colonies, possessed apparent oxidation activity toward coumarin and 7-ethoxycoumarin, which are typical human P450 substrates that produce fluorescent products. 7-ethoxycoumarin cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 When the P450 activities were measured at the whole-cell level, some of the blue colonies, but not the white colonies, possessed apparent oxidation activity toward coumarin and 7-ethoxycoumarin, which are typical human P450 substrates that produce fluorescent products. 7-ethoxycoumarin cytochrome P450 family 2 subfamily B member 6 Homo sapiens