Title : 17q12-21 - the pursuit of targeted therapy in breast cancer.

Pub. Date : 2010 May

PMID : 20100636






1 Functional Relationships(s)
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1 RESULTS: TOP2A has aroused particular interest as over-expression of its protein has been shown to correlate, both with amplification of HER2/neu, and with response to anthracycline-based chemotherapeutic agents in breast cancer. Anthracyclines DNA topoisomerase II alpha Homo sapiens