Pub. Date : 2010 Mar 30
PMID : 20100471
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OA ameliorated the oxidative injury induced by tBHP through increasing the generation of antioxidant (glutathione) and the expression of key antioxidant enzymes mediated by nuclear factorerythroid 2 p45-related factor 2 (Nrf2), in which process, activation of JNK and ERK, but not p38, was involved. | tert-Butylhydroperoxide | mitogen-activated protein kinase 1 | Homo sapiens |
2 | OA probably functions mainly through indirect biological effect and protects QZG cells against cytotoxicity induced by tBHP through increasing the generation of antioxidant and the expression of oxidative stress sensitive transcription factor-Nrf2, and MAP kinases, mainly JNK and ERK. | tert-Butylhydroperoxide | mitogen-activated protein kinase 1 | Homo sapiens |