Pub. Date : 2010 Feb 26
PMID : 20097169
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To study the enzymatic function of BACE, we mutated either of the two aspartic acid residues in the active site of BACE. | Aspartic Acid | beta-secretase 1 | Homo sapiens |
| 2 | To study the enzymatic function of BACE, we mutated either of the two aspartic acid residues in the active site of BACE. | Aspartic Acid | beta-secretase 1 | Homo sapiens |
| 3 | In contrast, substituting both active site aspartic acid residues produced a functionally inactive, endoplasmic reticulum-retained and partially glycosylated BACE. | Aspartic Acid | beta-secretase 1 | Homo sapiens |