Pub. Date : 2010 Mar
PMID : 20092437
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Large retrospective analyses of clinical data have repeatedly shown that diclofenac, similar as some selective COX-2 inhibitors, increases the propensity to experience adverse cardiovascular and atherothrombotic events. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | The reasons for this novel side-effect of diclofenac may be based on the specific pharmacology of diclofenac, which, similar to selective COX-2 inhibitors, alters vascular levels of platelet active prostaglandins in a way that favours arterial thrombosis. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | The reasons for this novel side-effect of diclofenac may be based on the specific pharmacology of diclofenac, which, similar to selective COX-2 inhibitors, alters vascular levels of platelet active prostaglandins in a way that favours arterial thrombosis. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |