Title : Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone.

Pub. Date : 2010 Apr

PMID : 20076952






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1 BACKGROUND: The aim of this study was to investigate the effects of the cytochrome P450 3A4 (CYP34A) inhibitor itraconazole on the pharmacokinetics and pharmacodynamics of orally and intravenously administered oxycodone. Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens