Title : Activation of phospholipase A2 by adriamycin in vitro. Role of drug-lipid interactions.

Pub. Date : 1991 Apr 5

PMID : 2007582






1 Functional Relationships(s)
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1 In the absence of added Ca2+ adriamycin caused a 3-4-fold activation of hydrolysis of this pyrenelipid whereas an inhibition of action of PLA2 on the corresponding phosphatidylcholine derivative C28-O-PHPC was observed. Phosphatidylcholines phospholipase A2 group IB Homo sapiens