Title : The NLRP3 inflammasome: a sensor for metabolic danger?

Pub. Date : 2010 Jan 15

PMID : 20075245






1 Functional Relationships(s)
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1 In doing so, we integrate previously disparate disease-driving mechanisms for IL-1beta, ROS, and TXNIP in T2DM into one unifying model in which the NLRP3 inflammasome plays a central role. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens