Title : Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.

Pub. Date : 2010 Feb

PMID : 20072130






1 Functional Relationships(s)
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1 The mTOR kinase functions in two complexes, TORC1 (target of rapamycin complex-1) and TORC2 (target of rapamycin complex-2); however, neither of these complexes is fully inhibited by the allosteric inhibitor rapamycin or its analogs. Sirolimus CREB regulated transcription coactivator 1 Homo sapiens