Title : Activation and induction of cytosolic phospholipase A2 by IL-1beta in human tracheal smooth muscle cells: role of MAPKs/p300 and NF-kappaB.

Pub. Date : 2010 Apr 1

PMID : 20069553






1 Functional Relationships(s)
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1 Cytosolic phospholipase A(2) (cPLA(2)) plays a pivotal role in mediating agonist-induced arachidonic acid (AA) release for prostaglandin (PG) synthesis during inflammation triggered by IL-1beta. Arachidonic Acid interleukin 1 beta Homo sapiens