Title : SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition.

Pub. Date : 2010 Mar 18

PMID : 20062077






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Instead, the inhibitory effect of SP600125 on mitotic entry predominantly occurs upstream of Aurora A kinase and Polo-like kinase 1, resulting in a failure to remove the inhibitory phosphorylation of Cdk1. pyrazolanthrone polo like kinase 1 Homo sapiens