Title : ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production.

Pub. Date : 2010 Jun

PMID : 20061533






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BCMO1 acts downstream of SR-BI and converts absorbed beta,beta-carotene to the retinoic acid precursor, retinaldehyde. beta Carotene beta-carotene oxygenase 1 Mus musculus
2 Using BCMO1-knockout mice, we demonstrated increased intestinal SR-BI expression and systemic beta,beta-carotene accumulation. beta Carotene beta-carotene oxygenase 1 Mus musculus