Title : Simvastatin induces derepression of PTEN expression via NFkappaB to inhibit breast cancer cell growth.

Pub. Date : 2010 May

PMID : 20060890






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We demonstrate that in the tumors derived from MDA-MB-231 human breast cancer cell xenografts, simvastatin significantly inhibited phosphorylation of Akt with concomitant attenuation of the expression of the anti-apoptotic protein Bcl(XL). Simvastatin AKT serine/threonine kinase 1 Homo sapiens