Title : Nuclear translocation of beta-actin is involved in transcriptional regulation during macrophage differentiation of HL-60 cells.

Pub. Date : 2010 Mar 1

PMID : 20053683






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we demonstrate that during the phorbol 12-myristate 13-acetate (PMA)-induced differentiation of HL-60 cells toward macrophages, beta-actin translocates from the cytoplasm to the nucleus and that this process is dramatically inhibited by pretreatment with p38 mitogen-activated protein kinase inhibitors. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 14 Homo sapiens
2 Here, we demonstrate that during the phorbol 12-myristate 13-acetate (PMA)-induced differentiation of HL-60 cells toward macrophages, beta-actin translocates from the cytoplasm to the nucleus and that this process is dramatically inhibited by pretreatment with p38 mitogen-activated protein kinase inhibitors. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 14 Homo sapiens