Title : Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism.

Pub. Date : 2009 Jun

PMID : 20049716






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These mutations demonstrate the importance of the gating loop of Kir channels in regulating Po((0)) and further suggest that Mg-nucleotide interaction with SUR1 may reduce ATP inhibition at Kir6.2. Adenosine Triphosphate ATP binding cassette subfamily C member 8 Homo sapiens