Title : A gene correcting the defect in the CHO mutant Ade -H, deficient in a branch point enzyme (adenylosuccinate synthetase) of de novo purine biosynthesis, is located on the long arm of chromosome 1.

Pub. Date : 1991 Feb

PMID : 2004783






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The Ade -H mutant is defective in the enzyme adenylosuccinate (AMPS) synthetase (ADSS; EC 6.3.4.4), which carries out the first of a two-step sequence in the biosynthesis of AMP from IMP, and therefore requires exogenous adenine for growth. Inosine Monophosphate adenylosuccinate synthase 2 Homo sapiens