Title : Collecting Duct Renin: A major player in Angiotensin II-dependent Hypertension.

Pub. Date : 2009 Mar-Apr

PMID : 20046983






1 Functional Relationships(s)
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1 This brief review is focused on recent evidence that inappropriate activation of renin in distal nephron segments, by acting on angiotensinogen generated in the proximal tubule cells and delivered to the distal nephron may contribute to increased distal intrarenal angiotensin II formation, sodium retention and development and progression of hypertension. Sodium renin Homo sapiens