Pub. Date : 2010 Jan 15
PMID : 20045648
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have taken advantage of the amino acid difference between the BACE1 and BACE2 at the S2" pocket (BACE1 Pro(70) changed to BACE2 Lys(86)) to build ligands with >500-fold selectivity against BACE2. | Lysine | beta-secretase 1 | Homo sapiens |