Title : Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis.

Pub. Date : 2010 Jan 22

PMID : 20043868






1 Functional Relationships(s)
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1 Simvastatin induced cardinal features of apoptosis including increased DNA fragmentation, disruption of mitochondrial membrane potential (MMP), and increased caspase-3 activity by depleting isoprenoids in MethA fibrosarcoma cells. Simvastatin caspase 3 Homo sapiens