Title : [Association study of the SCN1 gene polymorphism and effective dose of lamotrigine].

Pub. Date : 2009

PMID : 20037572






3 Functional Relationships(s)
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1 [Association study of the SCN1 gene polymorphism and effective dose of lamotrigine]. Lamotrigine sodium voltage-gated channel alpha subunit 1 Homo sapiens
2 An association between a polymorphism of the SCN1 gene, a therapeutical target of lamotrigine, and an effective dose (a blood plasma concentration) of the drug in patients with epilepsy has been studied. Lamotrigine sodium voltage-gated channel alpha subunit 1 Homo sapiens
3 The hypothesis on the association between the SCN1 IVS5N+5 G>A polymorphism and the effective dose (concentration) of lamotrigine was confirmed. Lamotrigine sodium voltage-gated channel alpha subunit 1 Homo sapiens