Title : Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition.

Pub. Date : 2010 Feb 26

PMID : 20032465






3 Functional Relationships(s)
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1 Sphingosine is known to inhibit protein kinase C (PKC), and PKC inhibition with nanomolar concentrations of staurosporine, calphostin C, and GF109203X down-regulated surface expression of S1P(1) but not S1P(4) in transfected rat hepatoma HTC(4) cells. Staurosporine protein kinase C, gamma Rattus norvegicus
2 Sphingosine is known to inhibit protein kinase C (PKC), and PKC inhibition with nanomolar concentrations of staurosporine, calphostin C, and GF109203X down-regulated surface expression of S1P(1) but not S1P(4) in transfected rat hepatoma HTC(4) cells. Staurosporine protein kinase C, gamma Rattus norvegicus
3 Sphingosine is known to inhibit protein kinase C (PKC), and PKC inhibition with nanomolar concentrations of staurosporine, calphostin C, and GF109203X down-regulated surface expression of S1P(1) but not S1P(4) in transfected rat hepatoma HTC(4) cells. Staurosporine protein kinase C, gamma Rattus norvegicus