Title : Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity.

Pub. Date : 2009 Dec 27

PMID : 20029328






1 Functional Relationships(s)
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1 Although the expression of aquaporin-2, NaPi-2, and paracellin-1 mRNAs tended to increase in kidneys with a reduced nephron mass, NaPi-2 mRNA levels decreased in 1/2K rats exposed to CsA/SRL for 28 days (P<0.05). Cyclosporine claudin 16 Rattus norvegicus