Title : Evaluation of the activity of P450 enzymes in rats: use of the single marker or combined drug administration.

Pub. Date : 2009

PMID : 20027151






1 Functional Relationships(s)
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1 DESIGN: In the presented work, the biotransformation rates of phenacetin and tolbutamide (markers of rat CYP1A2 and CYP2C6/11 metabolic activities, respectively) administered either separately or both simultaneously were compared. Phenacetin cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus