Title : Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival.

Pub. Date : 2010 Aug

PMID : 20023601






1 Functional Relationships(s)
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1 Our results show that after the onset of sepsis, tBid (the active form of Bid) is significantly increased in mitochondrial fractions of the thymus, spleen, Peyer patches, and liver, and that Fas or FasL deficiency blocks Bid activation in various tissues after septic challenge. tBID BH3 interacting domain death agonist Mus musculus