Title : Bile alcohols function as the ligands of membrane-type bile acid-activated G protein-coupled receptor.

Pub. Date : 2010 Jun

PMID : 20023205






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In a cell-based reporter assay and a cAMP production assay performed in vitro, most bile alcohols with a side chain containing hydroxyl group(s) were highly efficacious agonists for TGR5 comparable to its most potent ligand in the naturally occurring bile acid, lithocholic acid. Lithocholic Acid G protein-coupled bile acid receptor 1 Rattus norvegicus